Allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males or females aged 12 years and older; 2. Diagnosed with allergic rhinitis through typical clinical symptoms (recurrent sneezing, runny nose, nasal congestion, or nasal itching), and symptoms significantly occurring mainly in autumn; 3. Allergen testing results meet the following criteria: 1) Serum sIgE for weed pollen >= grade II or skin test >= " "; 2) Serum sIgE testing for dust mites, mold, and pets at grade 0 or skin test result "-";
Exclusion criteria
Exclusion criteria: 1.Patients with malignant tumors. 2.Those who are pregnant or breastfeeding. 3.Those who have other serious liver, kidney, heart, hematopoietic, nervous system or mental disorders. 4.Other conditions deemed unsuitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunoglobulin E, IgE;Mas related G protein-coupled receptor X2, MRGPRX2;Histamine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine test;Transcriptomic analysis;Metabolomics analysis;Cytokine level; | — |
Countries
China
Contacts
North China University of Science and Technology Affiliated Hospital