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Basic and clinical study and application of biomarkers of allergic rhinitis (MRGPRX2/IgER/H1R, etc.)

Basic and clinical study and application of biomarkers of allergic rhinitis (MRGPRX2/IgER/H1R, etc.)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102529
Enrollment
Unknown
Registered
2025-05-15
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis

Interventions

Group of patients with allergic rhinitis disease:None

Sponsors

North China University of Science and Technology Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Males or females aged 12 years and older; 2. Diagnosed with allergic rhinitis through typical clinical symptoms (recurrent sneezing, runny nose, nasal congestion, or nasal itching), and symptoms significantly occurring mainly in autumn; 3. Allergen testing results meet the following criteria: 1) Serum sIgE for weed pollen >= grade II or skin test >= " "; 2) Serum sIgE testing for dust mites, mold, and pets at grade 0 or skin test result "-";

Exclusion criteria

Exclusion criteria: 1.Patients with malignant tumors. 2.Those who are pregnant or breastfeeding. 3.Those who have other serious liver, kidney, heart, hematopoietic, nervous system or mental disorders. 4.Other conditions deemed unsuitable for inclusion by the researcher.

Design outcomes

Primary

MeasureTime frame
Immunoglobulin E, IgE;Mas related G protein-coupled receptor X2, MRGPRX2;Histamine;

Secondary

MeasureTime frame
Blood routine test;Transcriptomic analysis;Metabolomics analysis;Cytokine level;

Countries

China

Contacts

Public ContactNa Wang

North China University of Science and Technology Affiliated Hospital

229642285@qq.com+86 15324226391

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026