Postoperative pain after lumbar spine surgery
Conditions
Interventions
Control Group:Fentanyl 15 µg/kg + tropisetron 10 mg + normal saline was configured into a 300 ml patient-controlled analgesic pump. Intravenous fentanyl 2 µg/kg was injected 30 minutes before the oper
Fentanyl plus acetaminophen group:Fentanyl 10 µg/kg + acetaminophen 2 g + tropisetron 10 mg + normal saline were configured into a 300 ml patient-controlled analgesic pump. Acetaminophen 500mg was int
Fentanyl plus acetaminophen and flurbiprofen ester group:Fentanyl 10 µg/kg + acetaminophen 2 g + flurbiprofen cilexil 200 mg + tropisetron 10 mg + normal saline were configured into a 300 ml patient-c
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=65 years old, ASA grade I-III 2. Thoracolumbar interbody fusion 3. Surgery under general anesthesia 4. Can sign informed consent and have the ability to read and write.
Exclusion criteria
Exclusion criteria: 1. Refuse to participate in this experiment. 2. Emergency surgery. 3. Patients with incomplete data. 4. Those with severe dementia, speech impairment, hearing or visual impairment who are unable to complete the questionnaire. 5. Patients with severe cardiopulmonary, liver and kidney dysfunction before surgery. 6. Those with a history of chronic pain and long-term use of analgesic and sedative drugs. 7. Patients with mental illness and cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale,VAS;Pain;EQ-5D;PCS score;Mini Cog score;Indicators of liver function;Indicators of renal function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's anesthesia duration during surgery;Sex;Age;Body mass index; Analgesic pump usage;Blood count; | — |
Countries
China
Contacts
Public ContactWeixin Dai
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed