Recurrent corneal erosion
Conditions
Interventions
Epithelial debridement group:None
PTK group 1:None
PRK group 1:None
PTK group 2:None
PRK group 2:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria of recurrent corneal epithelial erosion. According to the following diagnostic criteria: a more than one attack of the same corneal epithelial defect without obvious inducement; b had a definite history of minor corneal trauma; c morning eye surface pain recurred; d Grayish white or rough surface lesions were found in some areas of the corneal epithelium. If condition a is met and one of conditions b-d is met, diagnosis can be made. 2.No previous surgical treatment was used; 3.Age >= 18 years old; 4.Agree to enter this study;
Exclusion criteria
Exclusion criteria: 1.Patients with a history of eye surgery; 2.Exclude eyelid structural abnormalities such as valgus, trichiasis and eyelid dysclosure; Infectious conjunctivitis or keratitis, glaucoma, thyroid related eye diseases, etc; 3.Serious primary diseases of cardiovascular, cerebrovascular, liver, kidney, endocrine and hematopoietic system, etc. Connective tissue diseases and severe autoimmune diseases, such as rheumatoid arthritis, sarcoidosis, lupus erythematosus, thyroiditis, etc.; Malignant tumor patients, etc. 4.Patients with scar constitution, patients with history of mental injury disorders, patients with intelligence defects, cognitive dysfunction, etc; 5.The treatment of drugs, anesthetic drugs, bandage mirror allergy; 6.Patients with contraindications to excimer laser surgery; 7.Do not agree to enter this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery time of healthy epithelium;Postoperative recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal epithelial thickness;Postoperative irritation symptoms; | — |
Countries
China
Contacts
Public ContactWu Shuangqing
Eye Hospital, Wenzhou Medical University
Outcome results
None listed