Meniere's disease (MD)
Conditions
Interventions
The Meniere Disease Group:NA
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnostic criteria: Meet the diagnostic criteria for Meniere's disease published by the American Academy of Otolaryngology Head and Neck Surgery (AO-HNS) in 2015, including typical episodes of vertigo (>=2, lasting 20 minutes to 12 hours), fluctuating hearing loss, tinnitus, or a feeling of stuffy ears. 2. Imaging examination: All patients were required to complete 3D-real IR sequence MRI examination 4 hours after intravenous injection of gadolinium contrast agent, and the image quality met the EH assessment requirements. 3. Clinical data integrity: Complete clinical data are available, including disease course (starting from the first diagnosis), symptom type (vertigo, tinnitus, ear tightness, hearing loss), pure tone hearing threshold measurement results (sub-low frequency, medium frequency, high frequency hearing loss), attack frequency (within the past 6 months), gender, age, etc.
Exclusion criteria
Exclusion criteria: 1. Other inner ear diseases (such as sudden deafness, vestibular neuritis, otosclerosis) Or central vertigo diseases (such as stroke, multiple sclerosis). History of ear surgery or trauma. 2. Gadolinium contrast allergy or MRI contraindications (e.g. metal implants, claustrophobia) Illness). 3. The clinical data is incomplete or the image quality does not meet the analysis requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The presence and severity of endolymphatic hydrops (EH);The affected areas of endolymphatic hydrops (EH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease course staging;Symptom type;Degree of hearing loss;Attack frequency;Demographic characteristics; | — |
Countries
China
Contacts
Public ContactCheng Weiling
The first affiliated hostipal of nanchang university
Outcome results
None listed