Mood disorders and Schizophrenia
Conditions
Interventions
Intervention group:Intervention group will receive an at least 5-day sleep-wake schedule delay.
Control group:None
Sponsors
Fuzhou Neuropsychiatric Hospital Affiliated to Fujian Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Is capable of giving informed consent; 3. Meet ICD-10 diagnostic criteria of mood disorders or schizophrenia; 4. Living in second-tier ward for at least 5 days.
Exclusion criteria
Exclusion criteria: 1. A current or past history of personality disorder, mental retardation, or organic mental disorder; 2. A current diagnosis of substance abuse or dependence; 3. Pregnant or breastfeeding women 4. Presence of eye disease: e.g. retinal blindness, severe cataract, glaucoma; 5. Currently receiving any medication(s) that may affect circadian rhythm (e.g., melatonin); 6. Night Shift worker or trans-meridian flight in the past 3 months and during study; 7. Significant medical condition/hearing impairment/speech or motor deficit; 8. Serious risk for self-harm or aggressive behaviors; 9. Currently under ECT treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rest-activity pattern measured by actigraphy;Objective chronotype (Melatonin onset based on saliva samples);Metabolism (Blood pressure and continuous glucose levels); | — |
Secondary
| Measure | Time frame |
|---|---|
| Mood symptoms (HAMD, YMRS);Insomnia symptoms (ISI);Psychotic symptoms (BPRS);Hypnotic use;Anxiety symptoms (HAMA);Subjective chronotype (rMEQ); | — |
Countries
China
Contacts
Public ContactJie Chen
Fuzhou Neuropsychiatric Hospital Affiliated to Fujian Medical University
Outcome results
None listed