Stroke,Cognitive impairment
Conditions
Interventions
True Stimulus Group:Receiving rTMS DLPFC true stimulation on the affected side
Pseudostimulus group:Acceptance of rTMS affected side DLPFC pseudostimulation
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In accordance with the diagnostic criteria for stroke in the "Guidelines for the Prevention and Treatment of Stroke in China (2021 Edition)," confirmed by cranial CT or magnetic resonance imaging; 2. Mini-Mental State Examination score: illiterate <= 17 points, primary school = 20 points, junior high school and above <=24 points; Montreal Cognitive Assessment score < 26 points. 3. Stable vital signs; 4. Informed consent, voluntary participation, informed consent form signed by the subject and their guardian.
Exclusion criteria
Exclusion criteria: 1. Individuals with consciousness disorders; those with severe hearing and visual impairments and inability to cooperate due to aphasia; individuals with immune system diseases, blood system diseases, and organ failure. 2. Subjects unable to cooperate in completing treatment due to other reasons. 3. Presence of contraindications for transcranial magnetic stimulation, such as intracranial metal implants, pacemakers, or a history of seizures. 4. Use of antibiotics or anti-inflammatory medications in the past month, and having taken probiotics in the past two months. 5. Participation in other clinical trials that may affect the final evaluation results of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG change;Brain function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mental status ;Cognition;Modified Barthel Index;Brain structure; | — |
Countries
China
Contacts
Public ContactZuoyan Liu
West China Hospital of Sichuan University
Outcome results
None listed