Allergic reactions
Conditions
Interventions
Perioperative anaphylactic shock (PAS) (experienced anaphylactic shock to rocuronium):None
Perioperative anaphylaxis(POA) (experienced anaphylactic tolerance to rocuronium):None
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Open to all genders; 2.Those who have undergone general anesthesia and have experienced anaphylactic shock or tolerance to rocuronium; 3.Those who exhibit a drop in blood pressure during the perioperative period, meeting the diagnostic criteria for a severe allergic reaction, with or without manifestations in other systems;
Exclusion criteria
Exclusion criteria: 1.Use of glucocorticoids during the perioperative period; 2.A drop in blood pressure during the perioperative period, with medical records indicating other confirmed causes of acute decompensation; 3.Individuals with incomplete medical records;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma Histamine Level;Plasma Tryptase Level;The lowest value of mean arterial pressure;rocuronium dosage for induction of general anesthesia;Types, doses, and timing of perioperative medications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of epinephrine; | — |
Countries
China
Contacts
Public ContactZheng Qi
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed