Malignant tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged >=18 years, pathologically diagnosed with gastrointestinal malignancies and scheduled to receive SOX or XELOX chemotherapy in a day-care setting. 2. Karnofsky Performance Status (KPS) score >=70. 3. No significant abnormalities in liver/kidney function, blood tests, or electrocardiogram (ECG) before chemotherapy. Hematological parameters must meet the following criteria: - Platelet count >85×10^9/L - White blood cell count >3.5×10^9/L - Neutrophil count >1.5×10^9/L - Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) <=3× the upper limit of normal (ULN) - Serum creatinine <=1.5× ULN - Total bilirubin <=1.5× ULN - No other contraindications to chemotherapy. 4. Patients scheduled to receive at least four consecutive cycles of day-care chemotherapy. 5. Willing to provide informed consent and able to complete follow-up via WeChat. 6. Capable of independently or with caregiver assistance completing the 'EORTC QLQ-C30' quality-of-life questionnaire.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot understand the research content. 2. Tumor patients who have changed their treatment methods or chemotherapy regimens. 3. Patients with mental disorders or those in an active phase of mental illness. 4. Patients who voluntarily discontinue anti-tumor chemotherapy or interrupt chemotherapy due to other severe medical conditions. 5. Patients with low compliance who cannot complete regular follow-ups.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Life ; | — |
Countries
China
Contacts
Ordos Central Hospital