none
Conditions
Interventions
DR Group:intranasal dexmedetomidine combined with intravenous remimazolam
DP Group:intranasal dexmedetomidine combined with intravenous propofol
Sponsors
Guangzhou Women and Children’s Medical Center, Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: These patients were aged 1 and 6 years, and had an American Society of Anesthesiologists (ASA) physical status of I–III. Furthermore, the planned imaging duration was not exceeding 60 minutes.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: unstable vital signs, severe cardiovascular, hepatic, or renal function impairment, active upper respiratory infection, severe obstructive sleep apnea syndrome (OSA) or other airway obstructive diseases, allergy history to dexmedetomidine or remimazolam, and patients having received any other sedative 48 hours before sedation. After enrollment, children who were successfully sedated with dexmedetomidine alone and did not require remimazolam or propofol were excluded from further analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation efficacy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| vital signs (Oxygen saturation, Heart rate, Blood pressure); | — |
Countries
China
Contacts
Public ContactWanjun Zheng
Guangzhou Women and Children’s Medical Center, Guangzhou Medical University
Outcome results
None listed