Insomnia
Conditions
Interventions
Didacini Formation Group:Insomniacs who are dissatisfied with traditional benzodiazepines (BZDs) are switched to didarzenil.
Sponsors
Anqing City Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-65 years old, gender is not limited; 2.Insomnia patients who have been taking estazolam, alprazolam, clonazepam, or lorazepam (only one of them) at least 3 nights a week within 2 weeks before the start of conversion treatment, and are not satisfied with the treatment effect or safety (overall satisfaction at baseline <4) and wish to switch to other drugs; 3.Intended to be treated with Ditarcini; 4.Ensure at least 7 hours of sleep; 5.Voluntary written informed consent.
Exclusion criteria
Exclusion criteria: 1.Presence of contraindications to didarzenil: including allergy to any vehicle of didarzenil, severe obstructive sleep apnea (OSA), respiratory insufficiency, or myasthenia gravis; 2.Treatment with two or more benzodiazepine receptor agonists; 3.Use of two or more drugs or health care products that regulate sleep function or affect sleep other than benzodiazepines within 7 days or less than 5 drug half-lives prior to enrollment; 4.Newly initiated non-pharmacological treatments for insomnia (e.g. cognitive behavioral therapy, physical therapy, etc.) within 1 week prior to the start of conversion therapy; 5.Women during pregnancy and lactation; 6.Other circumstances considered inappropriate by the investigator for participation in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Likert-7 points Overall Satisfaction Rating; | — |
Countries
China
Contacts
Public ContactHuang Dawei
Anqing City Sixth People's Hospital
Outcome results
None listed