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Exploring the effect pattern and mechanism of fire needle in treating kidney deficiency and blood stasis-type DOR infertility based on metabolomics

Exploring the effect pattern and mechanism of fire needle in treating kidney deficiency and blood stasis-type DOR infertility based on metabolomics

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102444
Enrollment
Unknown
Registered
2025-05-14
Start date
2023-07-20
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diminished Ovarian Reserve

Interventions

Intervention group:Electroacupuncture combined with fire needle
Non-intervention group:localized puncture
Health group:None

Sponsors

Nanjing Pukou Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 42 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of infertility caused by low ovarian reserve in traditional Chinese and Western medicine and the dialectic of traditional Chinese medicine is kidney deficiency and blood stasis type; (2) women of childbearing age aged 22-42 years; (3) No contraindications to hormone therapy and obvious heart, liver, kidney and other organ lesions; (4) The male reproductive function is normal; (5) Agree to accept treatment according to this protocol and follow-up observers; (6) Willing to sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Women who are already pregnant at the time of consultation; (2) Those who are allergic to acupuncture; (3) Patients with organic diseases, severe heart, liver, kidney damage, endocrine diseases and other pathologies that affect normal drug metabolism, menstruation, ovulation and fertility; (4) Patients with malignant tumors of genital organs undergoing surgical treatment and psychiatric diseases.

Design outcomes

Primary

MeasureTime frame
FSH (Follicle stimulating hormone);LH (luteinizing hormone);E2 (estradiol);AMH (Anti-Mullerian hormone);

Secondary

MeasureTime frame
TCM clinical symptom score;Perimenopausal symptom Scale;Self-rating Anxiety Scale;

Countries

China

Contacts

Public ContactZhu Qianyang

Nanjing Pukou Hospital of Traditional Chinese Medicine

zqy2738465571@163.com+86 188 4692 6614

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026