Hypoxemia
Conditions
Interventions
RF+RM:Rifentanil combined with remimazolam anesthesia.
AF+RM:The anesthesia protocol involves a combination of alfentanil and remimazolam.
AF+PR:A combination of Alfentanil and Propofol anesthesia.
RF+PR:Rifentanil combined with propofol anesthesia
Sponsors
Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18 - 65 years old; 2.Patients undergoing elective painless colonoscopy examination; 3.ASA classification 1-2 grade; 4.Agree to participate in this research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Refusal to participate in this study; 2. ASA III. or above; 3. BMI29.9kg/m^2; 4. History of chronic analgesic or sedative drug use, including benzodiazepines, alcohol abuse, allergy to propofol and remimazolam; 5. Electrocardiogram (ECG) suggests: heart rate 100 beats/min, or severe arrhythmia; 6. Those with a history of gastrointestinal diversion; 7. Cerebrovascular accident, myocardial infarction or unstable angina pectoris within the past 3 months; Severe liver and kidney dysfunction; Preoperative blood pressure >=180mmHg; 8. Participation in other research studies within the last 30 days; 9. Those who have a history of abnormal surgical anesthesia recovery in the past; 10. Those who predict that difficult airways may occur or have occurred, such as modified Mahalanobis class III.-IV;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of colonoscopy;Non-interventional inspection time;Incidence of body movement;Incidence OF RESCUE SEDATION;Changes in respiratory rate;Incidence of injection pain;Patient comfort and endoscopist satisfaction scores;Incidence of cough;Incidence of nausea and vomiting;Narcotic drug consumption; | — |
Countries
China
Contacts
Public ContactGu Xiaoping
Drum Tower Hospital
Outcome results
None listed