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The influence of intraoperative intravenous infusion of dexmedetomidine on postoperative sleep quality of patients undergoing gynecological laparoscopic surgery

The influence of intraoperative intravenous infusion of dexmedetomidine on postoperative sleep quality of patients undergoing gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102424
Enrollment
Unknown
Registered
2025-05-14
Start date
2025-05-19
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep-wake disorder

Interventions

Dexmedetomidine group:After induction of general anesthesia , the patient was given 0.4ug/ (kg·h) continuous intravenous pumping of dexmedetomidine for 30 minutes
Control group :No dexmedetomidine was administered after induction of anesthesia.

Sponsors

Haiyan People's Hospital,Jiaxing City,Zhengjiang Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range: 18 - 65 years old; ASA I-II grade; Patients undergoing gynecological laparoscopic surgery; This study must be approved by the hospital's ethics committee; All participating patients must sign the informed consent forms for anesthesia and the trial.

Exclusion criteria

Exclusion criteria: Body Mass Index (BMI) greater than 30; A clear history of psychiatric Sleep problems, such as depression, schizophrenia, sleep disorders (Pittsburgh Sleep Quality Index (PSQI) score >= 6), or a family history of sleep problems, cognitive impairment, or communication problems within three generations; In the past, the heart, liver, lung, kidney, endocrine and other important organ function damage; A recent history of substance abuse; In the past week, I have used central nervous system stimulants, sedatives, analgesics, hypnotics and drugs with similar pharmacological effects. Allergies to dexmedetomidine or contraindications (e.g., hypotension, heart rate <60 beats/min, heart block, etc.); Patients refused to participate in the study;

Design outcomes

Primary

MeasureTime frame
The incidence of sleep disorders on the first day after surgery;

Secondary

MeasureTime frame
Numeric rating scale of sleep ;Numeric rating scale of sleep ;Visual analogue pain score 72 hours after surgery;Use of sedative and analgesic drugs after surgery;

Countries

China

Contacts

Public ContactLin-Li

Haiyan People's Hospital,Jiaxing City,Zhengjiang Province

375404058@qq.com+86 158 8835 2036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026