After Liver Transplantation for Hepatocellular Carcinoma
Conditions
Interventions
The recurrence group after liver transplantation for hepatocellular carcinoma:None
The non-recurrence group after liver transplantation for hepatocellular carcinoma:None
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Recurrence Group: Patients who meet the Hangzhou criteria for liver transplantation for hepatocellular carcinoma (HCC); Patients with pathologically confirmed recurrence and metastasis more than six months after surgery; Patients who have not undergone antitumor chemotherapy or interventional therapy but may have received preventive targeted therapy; Patients who understand and sign the informed consent form. 2.Non-Recurrence Group: Patients who have no recurrence or metastasis for more than two years after surgery; Patients who may have received targeted therapy for recurrence prevention are also eligible; Patients who understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1). Patients who develop new tumors after surgery.;(2) Patients with a history of or currently concurrent other malignant tumors;(3) Patients with hepatocellular carcinoma (HCC) who experience recurrence or death within 3 months after liver transplantation; (4) Patients with abnormal liver or kidney function at present; (5) Patients who have undergone combined transplantation of multiple organs, such as the liver and kidney;(6) Patients with active tuberculosis infection; (7) Patients who are human immunodeficiency virus (HIV) positive;(8) Patients with a history of alcohol consumption, or consumption of probiotics or prebiotics within 1 week before sampling;patients who have undergone colonoscopy, intestinal enema treatment, or received antibiotic or traditional Chinese medicine treatment within 1 week before sampling; (9) Other factors that, in the judgment of the investigator, may affect the safety or compliance of the participant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal microbiota; | — |
Countries
China
Contacts
Public ContactShuhong Yi
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed