Erythematous capillarized rosacea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18-60; 2.Patients with a predominantly erythematous capillary-dilated phenotype diagnosed according to the latest diagnostic criteria of the American Rosacea Society (2017 edition); 3.Those who use type A recombinant type III combined with type X? humanized collagen as the main treatment modality;
Exclusion criteria
Exclusion criteria: 1.Patients who are pregnant, intending to become pregnant or breastfeeding; 2.Patients with comorbid acne at the time of consultation; 3.Patients who have taken oral antibiotics (e.g., minocycline, doxycycline), adrenergic receptor blockers (e.g., carvedilol), and other medications for rosacea (e.g., hydroxychloroquine, etc.) within the 4 weeks prior to treatment; patients who have been treated for rosacea with topical medications such as fusidic acid cream, azelaic acid, and brimonidine; patients who have undergone physiologic treatments for rosacea; and patients who have undergone treatments with salicylic acid and fructose acids; 4.Those taking oral retinoids within 2 months prior to treatment (6 months for a retinoids); 5.Patients treated with topical tacrolimus in the first 3 months of treatment; 6.Patients with a history of facial injections or surgery in the 2 months prior to treatment; 7.Treatment of malignant tumors and other serious underlying diseases, serious heart, brain, liver, kidney, lung, blood and other systemic diseases, autoimmune diseases, immunodeficiency, generalized muscular activity disorders; 8.Scarring, facial skin combined with various bacterial, fungal, viral and other infections; 9.Persons with incomplete medical records;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin physiological indicators (transepidermal water loss, skin oil, stratum corneum water content, melanin index, skin pH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index, DLQI;Global Aesthetic Improvement Scale; | — |
Countries
China
Contacts
The First Affiliated Hospital of Army Medical University