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A retrospective autocontrol study of type A recombinant type III combined with type X? humanized collagen in the treatment of erythematous capillary-dilated rosacea

A retrospective autocontrol study of type A recombinant type III combined with type X? humanized collagen in the treatment of erythematous capillary-dilated rosacea

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102377
Enrollment
Unknown
Registered
2025-05-14
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erythematous capillarized rosacea

Interventions

Rosacea patient group:None

Sponsors

The First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-60; 2.Patients with a predominantly erythematous capillary-dilated phenotype diagnosed according to the latest diagnostic criteria of the American Rosacea Society (2017 edition); 3.Those who use type A recombinant type III combined with type X? humanized collagen as the main treatment modality;

Exclusion criteria

Exclusion criteria: 1.Patients who are pregnant, intending to become pregnant or breastfeeding; 2.Patients with comorbid acne at the time of consultation; 3.Patients who have taken oral antibiotics (e.g., minocycline, doxycycline), adrenergic receptor blockers (e.g., carvedilol), and other medications for rosacea (e.g., hydroxychloroquine, etc.) within the 4 weeks prior to treatment; patients who have been treated for rosacea with topical medications such as fusidic acid cream, azelaic acid, and brimonidine; patients who have undergone physiologic treatments for rosacea; and patients who have undergone treatments with salicylic acid and fructose acids; 4.Those taking oral retinoids within 2 months prior to treatment (6 months for a retinoids); 5.Patients treated with topical tacrolimus in the first 3 months of treatment; 6.Patients with a history of facial injections or surgery in the 2 months prior to treatment; 7.Treatment of malignant tumors and other serious underlying diseases, serious heart, brain, liver, kidney, lung, blood and other systemic diseases, autoimmune diseases, immunodeficiency, generalized muscular activity disorders; 8.Scarring, facial skin combined with various bacterial, fungal, viral and other infections; 9.Persons with incomplete medical records;

Design outcomes

Primary

MeasureTime frame
Skin physiological indicators (transepidermal water loss, skin oil, stratum corneum water content, melanin index, skin pH);

Secondary

MeasureTime frame
Dermatology Life Quality Index, DLQI;Global Aesthetic Improvement Scale;

Countries

China

Contacts

Public ContactYin rui

The First Affiliated Hospital of Army Medical University

swyinrui@163.com+86 23 68766333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026