Anesthesia induction for post-induction hypotension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 60-80 years 2. ASA physical status classification II-III 3. Scheduled for non-cardiac surgery under general anesthesia 4. Meeting the diagnostic criteria for primary hypertension according to the *2018 Revised Edition of Chinese Guidelines for the Prevention and Treatment of Hypertension*
Exclusion criteria
Exclusion criteria: 1. Severe hepatic or renal dysfunction 2. Severe cardiovascular diseases (NYHA class >II, implanted pacemaker/cardioverter-defibrillator, unstable angina, or ejection fraction 30 kg/m² 8. Participation in other clinical trials within the past month 9. Preoperative hypovolemia (pulse pressure variation >10%) 10. Declined to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flow-Mediated Dilation;Hyperemic Velocity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basal heart rate;Basal mean arterial pressure;Post-induction heart rate;Post-induction mean arterial pressure;Postoperative nausea and vomiting;Postoperative Delirium;Postoperative Dizziness, Headache;Intraoperative vasoactive drug dosage;Intraoperative anesthetic drug dosage;Intraoperative blood loss;Intraoperative urine volume;Time of recovery;Time of extubation;PACU stay time; | — |
Countries
China
Contacts
Department of Anesthesiology, the Affiliated Hospital of North Sichuan Medical College