multiple system atrophy
Conditions
Interventions
MSA-P group:None
MSA-C group:None
healthy control group:None
Sponsors
Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.MSA group: 1) Age >35 years and gender; 2) Meets clinically confirmed MSA and clinically likely MSA according to the 2022 MDS MSA diagnostic criteria; 3) Voluntarily participated in this study and signed an informed consent form. 2.HC group: 1) Age, gender and other basic conditions matched with the MSA cohort population; 2) Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnancy or breastfeeding; 2. contraindications to MRI examination or inability to cooperate in completing neuroimaging examination; 3. previous history of other neurological disorders or presence of other organic intracranial lesions on neuroimaging that cannot be interpreted by MSA, such as epilepsy, trauma, tumors, or high-grade cerebral white matter degeneration (Fazekas grade 2 and above); 4.History of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standard uptake value ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity;specificity;accuracy; | — |
Countries
China
Contacts
Public ContactZhao Min
Third Xiangya Hospital of Central South University, Changsha, Hunan Province,China
Outcome results
None listed