Gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients voluntarily join this study and sign the informed consent form; 2. Age >=18 years old, = 12 months; 9. Normal function of major organs; 10. No absolute contraindications to surgery.
Exclusion criteria
Exclusion criteria: 1. Known HER2 positive; 2. History of previous gastric surgery; 3. Excisable during intraoperative exploration; 4. Combined organ resection; 5. Previous or concurrent other malignant tumors, except for cured basal cell carcinoma of the skin, carcinoma in situ of the cervix and carcinoma in situ of the breast; 6. Combined with severe illness and unable to tolerate surgery; 7. Those who have previously experienced gastrointestinal perforation, abdominal abscess, or recently (within 3 months) experienced intestinal obstruction or whose imaging and clinical symptoms suggest intestinal obstruction; 8. There are contraindications to the treatment of SOXAP regimen.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate;Postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| R0 resection rate;Objective response rate (ORR);Duration of surgery;Time to start chemotherapy after surgery;Adverse drug reactions;Assessment of pathological response;NRS2002 ratings;PG-SGA;OS;The cost of the surgery; | — |
Countries
China
Contacts
Cancer Hospital, Chinese Academy of Medical Sciences