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Evaluation of Ropivacaine versus Liposomal Bupivacaine Combined with Ropivacaine or Bupivacaine Hydrochloride for Postoperative Analgesia in Patients Undergoing Thoracoscopic Lung Cancer Resection

Evaluation of Ropivacaine versus Liposomal Bupivacaine Combined with Ropivacaine or Bupivacaine Hydrochloride for Postoperative Analgesia in Patients Undergoing Thoracoscopic Lung Cancer Resection: A Retrospective Case-Control Study:A retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102355
Enrollment
Unknown
Registered
2025-05-13
Start date
2025-05-26
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who underwent single-port thoracoscopic lung cancer resection after paravertebral nerve block

Interventions

Liposomal Bupivacaine mixed with Ropivacaine Group(Group L):None
Liposomal Bupivacaine Combined with Bupivacaine Hydrochloride Group (Group B):None
Ropivacaine Hydrochloride Group (Group R):None

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old and <= 65 years old; no restriction on gender; 2.Patients who underwent single-port thoracoscopic lung cancer resection after paravertebral nerve block; 3.ASA class I–II; 4.No hepatic or renal dysfunction; 5.No psychiatric disorders or cognitive impairments; 6.Received postoperative intravenous patient-controlled analgesia; 7.Had complete clinical data available for retrospective analysis;

Exclusion criteria

Exclusion criteria: 1.Patients with unclear ultrasound-guided paravertebral nerve block; 2.Patients with preoperative chronic opioid dependence or long-term use of various types of analgesics (more than 3 months), such as those with chronic low back pain; 3.Preoperative use of antipsychotic medications; 4.Alcohol and/or drug abuse; 5.Use of other drugs during surgery that may affect analgesia, such as esketamine or dexmedetomidine;

Design outcomes

Primary

MeasureTime frame
Postoperative Day 1 activity NRS pain intensity score;

Secondary

MeasureTime frame
NRS pain intensity rating;Postoperative pain pump sufentanil dosage;Supplementary dosage of pain relief medication in the ward;

Countries

China

Contacts

Public ContactSong Linlin

Peking University First Hospital

1131_1131@163.com+86 10 83575138

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026