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The impact of refractive anisometropia on visual function and dry eye after SMILE surgery.

The impact of refractive anisometropia on visual function and dry eye after SMILE surgery.

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102352
Enrollment
Unknown
Registered
2025-05-13
Start date
2025-04-06
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Visual function and dry eye after SMILE operation

Interventions

According to the severity of anisometropia, they were divided into non-anisometropia group, low anisometropia group (1.00D=SE2.50D), and intermediate-high anisometropia group (2.50D=SE6.00D).:The enro

Sponsors

China-Japan Union Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. The patient himself/herself has reasonable expectations of the SMILE procedure and is willing to remove the lens 3. Binocular spherical equivalent difference (spherical power + 1/2 x cylinder power) >=1.0D, corrected visual acuity >=0.8 4. No soft contact lens wear for one week and no aesthetic pupil wear for two weeks; 5. The refractive power of the patient is stable in the past two years (the annual refractive power increase is <=0.50D); 6. The patient was able to follow the postoperative instructions on time and review regularly.

Exclusion criteria

Exclusion criteria: 1. Age 0.50D per year); 5. Patients with vision-impacting cataract, severe dry eye, and uncontrolled glaucoma; 6. Active autoimmune and systemic connective tissue diseases, such as multiple sclerosis, systemic lupus erythematosus, etc.; mental symptoms such as depression and anxiety

Design outcomes

Primary

MeasureTime frame
Corneal Thickness;Tear film break-up time;positive and negative relative regulation;stereopsis;Eye position;

Countries

China

Contacts

Public ContactWang Shurong

China-Japan Union Hospital of Jilin University

srwang@jlu.edu.cn+86 181 8681 6291

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026