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The role and mechanism of TMEM40 in promoting malignant progression of colorectal cancer by upregulating tumor lipid metabolism through activation of TORC1 inhibited autophagy

The role and mechanism of TMEM40 in promoting malignant progression of colorectal cancer by upregulating tumor lipid metabolism through activation of TORC1 inhibited autophagy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102349
Enrollment
Unknown
Registered
2025-05-13
Start date
2025-02-12
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Colorectal cancer group:None

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The endoscopic findings and pathological diagnosis of the study participants met the diagnostic criteria for colorectal cancer; 2. The age range of the study participants is 40-80 years old, with no gender restrictions; 3. Voluntarily sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1.Previously received neoadjuvant chemotherapy or immunotherapy; 2.Merge severe cardiovascular and pulmonary diseases; 3.Combined coagulation dysfunction; 4.Not signing the informed consent form;

Design outcomes

Primary

MeasureTime frame
TMEM40;—

Countries

China

Contacts

Public ContactGuangre Xu

Sichuan Provincial People's Hospital

xgre@sina.com+86 15982408654

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026