Psoriasis
Conditions
Interventions
Merged fungal disease A:None
Non-merge of fungal disease A:None
Sponsors
Chengdu Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for psoriasis, accompanied by nail damage; 2. Diagnosed with psoriasis or psoriasis combined with onychomycosis through dermatoscopy or fungal microscopy/fungal culture; 3. Meets the indications for biologic therapy and can be followed up for at least 12 months; 4. The subject or the subject's guardian signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Contraindications related to biologics: (1) Allergy to active ingredients or other components of biologics; (2) Active infections (including active tuberculosis, highly active hepatitis virus infections, active periods of other viral infections, bacterial infections such as sepsis, etc.) and latent tuberculosis infections; (3) Congestive heart failure with a heart function classification of grade III or IV; (4) Merge with severe uncontrolled liver, lung, or kidney diseases; (5) Malignant tumors, excluding basal cell carcinoma of the skin and tumors with a treatment response period of>=10 years; (6) History of demyelinating syndrome or multiple sclerosis in the past; (7) Congenital or acquired immunodeficiency status; 3. Individuals who have previously been allergic to biologics or antifungal drugs; 4. Other factors that the researcher deems unsuitable for inclusion in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NAPSI Score; | — |
Countries
China
Contacts
Public ContactBin Yin
Chengdu Second People's Hospital
Outcome results
None listed