colonic polyps
Conditions
Interventions
Test group:According to the Dixon sequential method, the initial dose of continuous infusion of cyclosporine in the first patient was 1mg/kg/h. The dosage for the next patient was determined by the re
Sponsors
Shanghai Xuhui Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age range of 65 to 75 years old; 2. Patients planning to undergo ESD surgery for colon polyps; 3. Surgery time within 1 hour; 4. The American Society of Anesthesiologists (ASA) classifies it as Grade I-II; 5. Body Mass Index (BMI) is between 20-25; 6. Mallampati is classified as grades I-II;
Exclusion criteria
Exclusion criteria: 1. Patients with serious systemic diseases, such as liver and kidney dysfunction, cardiovascular and cerebrovascular diseases, immune system diseases, etc; 2. Having a history of alcoholism, drug dependence, mental illness, or neurological disorders (such as Alzheimer's disease, stroke, and abnormal psychology); 3. Changes in surgical procedures due to patient reasons; 4. Individuals who are allergic to ketamine or cyclosporine and any ingredients in their formulations; 5. Merge upper respiratory tract abnormalities that may lead to respiratory distress, respiratory dysfunction, or sleep apnea.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Dosage of cyclopofol while Postive reaction occures; | — |
Secondary
| Measure | Time frame |
|---|---|
| wake-up time;Hemodynamic indicators;Intraoperative adverse reactions;Total dosage of ciprofol during surgery;Dosage of vasoactive drugs during surgery;Anesthesia onset time;SPO2; | — |
Countries
China
Contacts
Public ContactIlyar Mamtili
Shanghai Xuhui Central Hospital
Outcome results
None listed