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Neural Correlates of Cognitive Deficit in Emotional Directed Forgetting in Major Depressive Disorder: An Event-Related Potential Study

Neural Correlates of Cognitive Deficit in Emotional Directed Forgetting in Major Depressive Disorder: An Event-Related Potential Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102325
Enrollment
Unknown
Registered
2025-05-13
Start date
2021-03-04
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder

Interventions

Depressed patients group:None
Healthy control group:None

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Depressive disorders: inclusion criteria 1. Complies with ICD-11 diagnostic criteria for depressive disorders HAMD-24 rating>20 3. Age between 18-65 years old; Right-handed 4. Han ethnicity; 5. Correct visual acuity>1.0 6. Understand the content and requirements of this study, inform each participant in detail of the trial purpose, methods, procedures, and possible discomfort and risks before the trial, and voluntarily participate in this study and sign an informed consent form. Normal control group: 1. Han Chinese; 2. Age between 18-65 years old, right-handed; HAMD-24 score1.0; 5. Understand the content and requirements of this study, voluntarily participate in this study, and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Serious physical illnesses, history of traumatic brain injury, substance dependence and abuse, and other diseases that can lead to cognitive impairment; 2. Those who have received shock free electroconvulsive therapy; 3. Individuals with severe cognitive impairment, psychiatric symptoms, bipolar disorder, generalized anxiety disorder, and attention deficit disorder; 4. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Amplitude;Latency;

Countries

China

Contacts

Public ContactXiaoting Zhou

Wuxi Mental Health Center

zxt819701909@sohu.com+86 189 2122 5286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026