Diffuse adenomyosis (DAD) and diffuse uterine leiomyomatosis (DUL)
Conditions
Interventions
Diffuse uterine myomatosis group:NA
DAD group with intramuscular lesions:NA
DAD group with external muscle layer lesions:NA
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. disease severity: (1) clinical symptoms: severe dysmenorrhea, visual blur score >= 7, requiring analgesic drugs; (2) Degree of lesion: uterus with diffuse adenomyosis >= 70 days of gestation (volume>100cm^3), and the lesion involved more than 80% of the anterior and/or posterior myometrium, or the myometrium thickened by more than 6cm. 2. age and infertility history: (1) age 20-45 years old, married, with fertility requirements; (2) Infertility for more than 2 years, has tried various assisted pregnancy techniques without success; (3) Ovarian reserve function is normal (Note: AMH >= 1.09 is included in fertility assessment, and AMH decline can be included but fertility analysis is not conducted), and it is not complicated with uterine malformation, intrauterine model damage adhesion syndrome and other uterine infertility. 3. meet the above inclusion criteria, and voluntarily accept push surgery without contraindications.
Exclusion criteria
Exclusion criteria: 1. suffering from severe internal and external diseases, unable to tolerate surgery, in any acute stage of systemic inflammation, pregnancy, lactation or accompanied by malignant tumors; 2. none of the above inclusion criteria is included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intravenous hysterography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dysmenorrhea;Tumor indicators; | — |
Countries
China
Contacts
Public ContactChangzhong Li
Peking University Shenzhen Hospital
Outcome results
None listed