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Construction of a predictive model for hospital-acquired pneumonia risk in patients with mild traumatic brain injury based on Lasso-Logistic regression

Construction of a predictive model for hospital-acquired pneumonia risk in patients with mild traumatic brain injury based on Lasso-Logistic regression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102320
Enrollment
Unknown
Registered
2025-05-13
Start date
2024-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury-associated pneumonia

Interventions

HAP group/Non-HAP group:None

Sponsors

Changzhou Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-65; 2.Head trauma with a first diagnosis of craniocerebral injury made within 24 h of admission and confirmed by imaging on admission; 3.Patients with a GCS score of 13-15 and a post-injury coma time of <20 min; 4.Clinical electronic case information is accessible to those who are able to access it.

Exclusion criteria

Exclusion criteria: 1.Patients who have developed a pulmonary infection prior to admission; 2.Those with concurrent cranial tumors or combined cerebrovascular disease; 3.Patients with a combination of other acute and chronic infectious diseases, immunodeficiency or autoimmune diseases, blood disorders and tuberculosis; 4.Patients transferred to neurosurgery from other departments during hospitalization; 5.Patients with >30% missing values in clinical variables identified after admission; 6.Patients with incomplete clinical data and hospitalization <48 hours.

Design outcomes

Primary

MeasureTime frame
Injury causative factors (falls, traffic accidents, others);Blood uric acid (UA);Sex;Prothrombin time (PT);C-reactive protein (CRP);Procalcitonin (PCT);Neutrophil count (NEUT);Erythrocyte sedimentation rate (ESR);Fibrinogen equivalent units (FEUs);Fibrinogen (FBG);Hematocrit (HCT);Hemoglobin (Hb);Platelet count (PLT);Blood Glucose (GLU);Serum sodium (Na);Serum potassium (K);Age;Maximum body temperature (MaxT);Maximum heart rate (MaxHR);Highest systolic blood pressure (MaxSBP);Lowest systolic blood pressure (MinSBP);Maximum respiratory rate (MaxRR);Hypertension;Diabetes;Admission source (outpatient, emergency);Activated partial thromboplastin time (APTT);Total cholesterol (TC);Lactate Dehydrogenase (LDH);Albumin (ALB);Prealbumin (PAB);Blood creatinine (CREA);Blood Urea Nitrogen (BUN);Total Bilirubin (TBIL);—

Countries

China

Contacts

Public ContactQin Hui

Changzhou Second People's Hospital

13776813323@139.com+86 519 81099988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026