Granulomatous Mastitis
Conditions
Interventions
Disease Group:None
Control Group:None
Sponsors
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Disease Group (Case Group): (1) Non-lactating, non-pregnant females; (2) Aged 25–40 years; (3) Meeting the diagnostic criteria of Liver Channel Stagnation-Heat Syndrome () or Phlegm-Heat Stasis Syndrome () for granulomatous mastitis according to Traditional Chinese Medicine (TCM) Guidelines; (4) Pathologically confirmed granulomatous mastitis; (5) No ulceration or skin breakdown in the affected breast; (6) Informed consent obtained, with voluntary participation and signed informed consent form. 2. Control Group: (1) Non-lactating, non-pregnant females; (2) Aged 25–40 years; (3) In good general health, without diagnosed systemic diseases, and not undergoing medical treatment; (4) Pathologically confirmed breast fibroadenoma, breast cyst, or hyperplasia; (5) Informed consent obtained, with voluntary participation and signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have received treatment with glucocorticoids, antibiotics, and immunosuppressants in the past month; 2. Suffering from duodenal ulcer, gastric ulcer, gastric bleeding or other gastrointestinal diseases; 3. Patients with serious primary diseases such as liver, heart, kidney, lung, hematopoietic system, and mental illness; 4. Suffering from immune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and autoimmune skin diseases; 5. History of other confirmed infections within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine ;CRP;Erythrocyte sedimentation rate;Immune globulin;Lymphocyte subpopulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Temperature;Heart rate;Breath rate;Blood pressure;Serum biochemical indicators;Blood fat;Sex hormone;Cytokines; | — |
Countries
China
Contacts
Public ContactHongfeng Chen
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed