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Application of Different Doses of BupivacaineApplication of Different Doses of Liposomal Bupivacaine in Interscalene Brachial Plexus Block for Arthroscopic Shoulder Surgery: A Single-Center Prospective Randomized Controlled Study

Application of Different Doses of Liposomal Bupivacaine in Interscalene Brachial Plexus Block for Arthroscopic Shoulder Surgery: A Single-Center Prospective Randomized Controlled Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102309
Enrollment
Unknown
Registered
2025-05-13
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain After Shoulder Surgery

Interventions

LB1 group:Performing interscalene brachial plexus block using 66.5 mg of liposomal bupivacaine.
LB2 group:Performing interscalene brachial plexus block using 99.75 mg of liposomal bupivacaine.
LB3 group:Performing interscalene brachial plexus block using 133 mg of liposomal bupivacaine.

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) ASA classification levels I to III; (2) Scheduled arthroscopic shoulder surgery; (3) Body mass index (BMI) 20 to 30 kg/m^2; (4) Age 18 to 65 years; (5) Participants voluntarily join the study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Severe functional impairment of important organs; (2) Allergy to the study drug; (3) Pregnancy; (4) Severe coagulopathy; (5) Skin infection at the puncture site; (6) Inability to communicate preoperatively due to visual, auditory, language, or other reasons.

Design outcomes

Primary

MeasureTime frame
Postoperative Motor Recovery Time;

Secondary

MeasureTime frame
Postoperative Visual Analogue Scale score;Postoperative rescue drug dosage;Postoperative Quality of Recovery Score - 15;Postoperative Adverse Events;

Countries

China

Contacts

Public ContactZhang Lizi

Shenzhen Second People's Hospital

lizdoc@163.com+86 185 7669 5366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026