Ovarian cancer
Conditions
Interventions
Gold Standard:Reference Standard: The efficacy of neoadjuvant chemotherapy in patients was assessed according to the Response Evaluation Criteria in Solid Tumors (RECIST 1.1).
Index test:Quantitative parameters of contrast-enhanced ultrasound: peak intensity (PI), time to peak (TTP), rise time (RT), mean transit time (MTT), wash-in rate (WIR), and area under the curve (AUC)
Sponsors
PEKING UNIVERSITY SHENZHEN HOSPITAL
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with ovarian cancer (pathological type: epithelial ovarian cancer) and scheduled to receive neoadjuvant chemotherapy; 2.Aged at least 18 years old; 3.Capable of cooperating to complete contrast-enhanced ultrasound examinations; 4.All participants provided informed consent and signed the corresponding informed consent form;
Exclusion criteria
Exclusion criteria: 1.With severe cardiorespiratory diseases; 2.Inadequacy of hepatic and renal functions; 3.Pregnant or lactating women; 4.Postoperative recurrent patients; 5.Patients diagnosed with ovarian cancer (non-epithelial pathological type);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak intensity (PI);Time to peak (TTP),;Rise time (RT);Mean transit time (MTT);Wash-in rate (WIR);Area under the curve (AUC);Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive predicative value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactRuijie Sun
Peking University Shenzhen Hospital
Outcome results
None listed