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Study on the Effect of Social Isolation on the Treatment of Depression

Study on the Effect of Social Isolation on the Treatment of Depression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102283
Enrollment
Unknown
Registered
2025-05-12
Start date
2025-08-30
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive disorder

Interventions

Social isolation group:None
Normal social group:None

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age range is 18-65 years old; 2.Currently, it meets the diagnostic criteria for depression in DSM-5; 3.Currently preparing to use SSRI/SNRI class drugs for antidepressant treatment; 4.Capable of reading and understanding Chinese, and able to use electronic devices; 5.Agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Previously defined manic or hypomanic episodes; 2.Individuals with previously diagnosed schizophrenia, schizophrenia, and other comorbid mental disorders; 3.Patients with a history of alcohol or drug dependence and acute poisoning in the past; 4.Pregnant or lactating female patients; 5.Researchers believe that patients currently have a serious risk of suicide, with a HAMD-17 suicide risk score of >= 3; 6.At present, researchers with serious physical illnesses believe that it is not suitable to be included in this study.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression ;Hamilton Anxiety;Montgomery-Depression;Social Network Index,SNI;Interpersonal Support Evaluation ;ULCA;Interview on Mental Disorders;Social isolation interviews;

Secondary

MeasureTime frame
EQ-5D-5L;2-back?PVT?Emotion Stroop?Emotional Memory Task;Mini-Mental State;Pittsburgh sleep quality index,PSQI;Body Movement Recorder Indicators;

Countries

China

Contacts

Public ContactYuhan Zhao

Nanfang Hospital, Southern Medical University

376946332@qq.com+86 20 6164 2066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026