Painless gastroscopy and colonoscopy
Conditions
Interventions
The group treated with alfentanil combined with propofol (AP group):During the induction period, 7 µg/kg of alfentanil was slowly injected intravenously, and then 10 seconds after the intravenous inje
Sponsors
Jiangxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective painless gastro-intestinal endoscopy; 2. Age range: 18 - 60 years old, gender not limited; 3. Body Mass Index (BMI): 18 - 29 kg/m2; 4. ASA grade I - III; 5. Participants voluntarily participated in this study and signed the informed consent form of this study.
Exclusion criteria
Exclusion criteria: 1. Those allergic to opioid drugs, benzodiazepine drugs, propofol, flumazenil or naloxone excipients; 2. Those suspected of abusing narcotic analgesics or sedatives, as well as alcoholics; 3. Those with severe arrhythmia; 4. Those with a history of acute respiratory tract infection within 2 weeks and unhealed disease; 5. Those with a history of serious heart, brain, lung, liver, kidney or metabolic diseases; 6. Those with neuromuscular system diseases (such as myasthenia gravis); 7. Those with mental disorders; 8. Those with preoperative hypertension with systolic blood pressure > 180 mmHg and/or diastolic blood pressure > 110 mmHg, or hypotension with < 90/60 mmHg; 9. Those who are predicted to have or have had difficult airways, such as modified Mallampati grade III-IV; 10. Pregnant or lactating women and those with a fertility plan within 3 months (including males); 11. Other subjects that the researchers consider not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor function grading;Awakening time;Satisfaction rating; | — |
Countries
China
Contacts
Public ContactMingsheng Zhang
Jiangxi Provincial People's Hospital
Outcome results
None listed