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Investigation of the Role and Clinical Significance of Altered Platelet Marker Expression in Thrombus Formation

Investigation of the Role and Clinical Significance of Altered Platelet Marker Expression in Thrombus Formation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102271
Enrollment
Unknown
Registered
2025-05-12
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombotic diseases

Interventions

Observation group:None
Control group:None

Sponsors

The Third Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Clinical suspicion of thrombotic disorders: 1. Meet the clinical diagnostic criteria for the diagnosis of acute thrombotic diseases (such as suspected PTE, AMI, IS, etc., see the Guidelines for the Prevention and Treatment of Thrombotic Diseases in China 2018 for specific diagnostic criteria); 2. Within 48 hours of onset, age 18-80 years old; 3. Informed consent and signed written consent. Healthy control group: 1. Match the age and gender of the patient group; 2. No history of cardiovascular and cerebrovascular diseases, no other blood and immune system diseases; 3. No obvious abnormalities were found in the physical examination; 4. Informed consent and signed written consent.

Exclusion criteria

Exclusion criteria: 1. Long-term treatment with antiplatelet drugs (aspirin, clopidogrel, ticagrelor, etc.); 2. Combined with severe infection, sepsis or other serious systemic diseases; 3. Pregnant and lactating females; 4. Those with a history of severe liver and kidney dysfunction or malignant tumors; 5. Those with a history of recent surgery or trauma.

Design outcomes

Primary

MeasureTime frame
Platelet markers;Platelet aggregation function;Platelet count;

Secondary

MeasureTime frame
Ejection fraction of the heart;Glasgow Coma Scale Score;Length of hospital stay;

Countries

China

Contacts

Public ContactJie Chen

The Third Affiliated Hospital of Wenzhou Medical University

woshichenjie@126.com+86 135 8740 9966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026