Prostate cancer
Conditions
Interventions
Intervention group:Collect venous blood for PSA screening tests in the intervention group. Biological specimens for testing should be properly preserved as required, testing should be completed within
those with PSA >= 4.0 ng/ml will undergo further clinical examination and intervention under the guidance of a clinician. Those with PSA < 4.0 ng/ml will have a test and follow-up every 2 years, conti
Control group:None
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
Male
Age
55 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Male2. Age 55-74 years3. Local registered permanent residents of the study area (living locally for six months or more)4. Sign the informed consent form and agree to participate in this study.
Exclusion criteria
Exclusion criteria: 1. History of cancer or received any type of cancer-related treatment (except for non-melanoma skin cancer); 2. PSA test conducted within the past 2 years; 3. Suffering from other serious illnesses that may affect the benefits of screening (such as stroke, severe lung disease, end-stage kidney disease, end-stage liver disease, severe heart failure, etc.); 4. Rectal examination, cystoscopy, catheterization or similar procedures performed within the last 48 hours; 5. Ejaculation occurred within the last 24 hours; 6. Suffering from prostatitis, or had prostatitis but cured for less than two weeks; 7. Taking medications for benign prostatic hyperplasia (such as finasteride, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prostate cancer mortality;Detection of clinically insignificant prostate cancer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Prostate cancer mortality;Incidence of prostate cancer ;clinically significant prostate cancer;Clinically advanced or high-risk prostate cancer;Difference in TNM stage;Survival for non-metastatic prostate cancer;All cancer mortality;All-cause mortality;Cost-effectiveness; | — |
Countries
China
Contacts
Public ContactWanqing Chen
Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed