The effect of altitude on induction and recovery of general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) ASA I-II classification; 2) Age 18-65 years; 3) Planned to undergo non-cardiac surgery under general anesthesia; 4) Planned to conduct CSI monitoring in the operating room; 5) Able to understand and cooperate with this study and provide informed consent.
Exclusion criteria
Exclusion criteria: 1.Diagnosed with cognitive impairment diseases, mental illness, neurological disorders; or having pre-existing symptoms of cognitive impairment or unconsciousness; or taking medication related with mental illness treatment for a long time; 2.Alcoholic addiction, severe sleep disorder; or hypnotic or other drug dependency; 3.History of postoperative adverse reactions associated with anesthesia; allergic to anesthetic drugs or CSI monitering patch material; 4.Incomplete medical record; 5.Preoperative, intraoperative or postoperative CSI monitering interruption, or data loss; 6.Transferred to ICU after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery time after general anesthesia surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of anesthesia induction;Anesthesia drugs;Time of tracheal intubation removal;Time in the post-anesthesia care unit;Electromyography (EMG);Delayed recovery;Intraoperative inflow and outflow;Modified Aldrete Scoring System;Other sedation related adverse events after surgery;Operative time;Cerebral stata index (CSI);Postoperative respiratory and circulatory fluctuations;Intraoperative awareness;burst inhibition ratio (BS%);Time of consciousness loss;Vital sign;Time of Anesthesia maintenance;Postoperative acute brain dysfunction; | — |
Countries
China
Contacts
Peking Union Medical College Hospital