Hypotension after spinal anesthesia
Conditions
Interventions
Sequentially allocated:The starting rescue dose was 0.05 µg/kg, and the remedial dose was increased by 0.025 µg/kg each time after failure of prophylaxis, with an upper limit of 0.15 µg/kg
if the remedial dose was successful, the next remedial dose was a reduction of 0.025 µg/kg with a 1/9 probability, and the original dose with a lower limit of 0.05 µg/kg with an 8/9 probability.
Sponsors
Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Patients scheduled for elective cesarean section under spinal anesthesia (single fetus, term pregnancy, aged 18–45 years)
Exclusion criteria
Exclusion criteria: Hypertension, severe liver or kidney diseases, cardiovascular and cerebrovascular diseases, height 180 cm, body weight 100 kg, coagulation dysfunction, baseline systolic blood pressure <100 mmHg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rates of different rescue doses; | — |
Secondary
| Measure | Time frame |
|---|---|
| Block level;Time from skin incision to fetal delivery;Time from anesthesia induction to fetal delivery;Heart rate;Pulse oxygen saturation;Pressure;Mean arterial pressure;Fetal Apgar score;Umbilical artery blood gas analysis; | — |
Countries
China
Contacts
Public ContactWenyuan Lyu
Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University
Outcome results
None listed