Schizophrenia
Conditions
Interventions
Intervention Group:Digital Cognitive Training
Control Group:computer games
Sponsors
Peking University Sixth Hospital (Institute of Mental Health)
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of schizophrenia according to DSM-5 criteria (clinical interview/medical record documentation). 2. Stable condition for >= 3 months, without the need for increased psychiatric rehabilitation care due to worsening of schizophrenia. 3. Age 18-50 years. 4. Ability to understand and read Chinese, comprehend the testing procedures, and use a tablet for cognitive training. 5. Ability to understand the informed consent content and study procedures, and to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Presence of other diseases that may affect cognitive function, including but not limited to: intellectual disability, dementia, or head trauma with loss of consciousness exceeding 1 hour. 2. Presence of severe motor incoordination (including extrapyramidal symptoms caused by antipsychotic medications). 3. Presence of suicide risk (suicidal behavior within the past year, suicidal ideation or attempts within the past 3 months). 4. Received MECT (modified electroconvulsive therapy) within the past six months. 5. Recently received or are currently receiving other treatments that may affect cognitive function (at the discretion of the investigator): including clozapine, ketamine, stimulants, potent or moderate CYP3A4 inhibitors/inducers; antiepileptic drugs, tricyclic antidepressants, traditional Chinese medicine/non-Western medicine that may affect cognition, dietary supplements and herbs, rTMS (repetitive transcranial magnetic stimulation), cognitive training, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese Brief Cognitive Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Personal and Social Performance Scale;Schizophrenia Cognition Rating Scale; | — |
Countries
China
Contacts
Public ContactChuan Shi
Peking University Sixth Hospital(Institute of Mental Health)
Outcome results
None listed