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Risk Factor Analysis of Delayed Cerebral Ischemia in Patients with Severe Subarachnoid Hemorrhage: An Observational Cohort Study

Risk Factor Analysis of Delayed Cerebral Ischemia in Patients with Severe Subarachnoid Hemorrhage: An Observational Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102207
Enrollment
Unknown
Registered
2025-05-12
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid Hemorrhage

Interventions

DCI group:This was an observational study without intervention
all patients received standard conventional treatment.
Non-DCI group:This was an observational study without intervention

Sponsors

The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Adult patients with severe aneurysmal subarachnoid hemorrhage admitted to the aforementioned wards. Inclusion Criteria: 1. Age >= 18 years and <= 85 years; 2. Aneurysmal subarachnoid hemorrhage; 3. Hunt-Hess (H-H) grade: 2 to 5.

Exclusion criteria

Exclusion criteria: 1. previous history of subarachnoid hemorrhage, prior decompressive craniectomy, cerebrospinal fluid leakage or drainage; 2. bilaterally fixed or dilated pupils; 3. hemodynamic instability; 4. hemoglobin less than 8 g/L; 5. serum osmolality greater than 320 mOsm/L; 6. severe dysfunction of vital organs such as the heart, lungs, liver, or kidneys; 7. severe electrolyte disturbances (serum sodium less than 125 mmol/L or greater than 170 mmol/L) that could not be corrected in a short period; 8. severe acid-base imbalance that could not be quickly corrected; 9. use of antiplatelet or anticoagulant drugs; 10. pregnancy.

Design outcomes

Primary

MeasureTime frame
Delayed cerebral ischemia;

Secondary

MeasureTime frame
modified Rankin Scale (mRS) at 3 months after discharge;GOS at 3 months after discharge;modified Rankin Scale (mRS) at 6 months after discharge;GOS at 6 months after discharge;

Countries

China

Contacts

Public ContactWu Wen

The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital

fly5wing@126.com+86 189 7151 9239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026