Subarachnoid Hemorrhage
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients with severe aneurysmal subarachnoid hemorrhage admitted to the aforementioned wards. Inclusion Criteria: 1. Age >= 18 years and <= 85 years; 2. Aneurysmal subarachnoid hemorrhage; 3. Hunt-Hess (H-H) grade: 2 to 5.
Exclusion criteria
Exclusion criteria: 1. previous history of subarachnoid hemorrhage, prior decompressive craniectomy, cerebrospinal fluid leakage or drainage; 2. bilaterally fixed or dilated pupils; 3. hemodynamic instability; 4. hemoglobin less than 8 g/L; 5. serum osmolality greater than 320 mOsm/L; 6. severe dysfunction of vital organs such as the heart, lungs, liver, or kidneys; 7. severe electrolyte disturbances (serum sodium less than 125 mmol/L or greater than 170 mmol/L) that could not be corrected in a short period; 8. severe acid-base imbalance that could not be quickly corrected; 9. use of antiplatelet or anticoagulant drugs; 10. pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delayed cerebral ischemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| modified Rankin Scale (mRS) at 3 months after discharge;GOS at 3 months after discharge;modified Rankin Scale (mRS) at 6 months after discharge;GOS at 6 months after discharge; | — |
Countries
China
Contacts
The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital