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Correlation analysis of awakening and propofol plasma concentration during scoliosis correction surgery: A single-center, observational study

Correlation analysis of awakening and propofol plasma concentration during scoliosis correction surgery: A single-center, observational study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102189
Enrollment
Unknown
Registered
2025-05-09
Start date
2025-05-12
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent scoliosis

Interventions

Propofol monitoring group:none

Sponsors

Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 10 years old and <= 18 years old; 2. ASA classification I-III; 3. Scheduled to undergo spinal orthopedic surgery; 4. Need for intraoperative awakening; 5. Agree to participate in this research and sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in this research; 2. Severe liver dysfunction (Child-Pugh C grade); Severe renal dysfunction (preoperative dialysis was received); ASA classification >= IV grade; 3. The preoperative assessment indicated that the patient was unable to cooperate for the completion of intraoperative awakening or had language communication disorders. 4. Allergy to Propofol; 5. Other researchers or attending physicians consider that certain situations are not suitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
Plasma concentration of propofol;Bispectral index;

Secondary

MeasureTime frame
The time from awakening and stopping medication during surgery to awakening;The dosage of anesthesia drugs used during surgery;Intraoperative wake-up quality score;Intraoperative awareness of incidence rate;

Countries

China

Contacts

Public ContactJinhua Bo

Drum Tower Hospital

15951987578@126.com+86 15951987578

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026