Postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA classification I-III; 2. Age >= 65 years; 3. Scheduled surgery with planned subarachnoid block anesthesia; 4. Preoperative screening using the Mini-Mental State Examination (MMSE) (maximum score 30), with scores of 17 or above for illiterate (uneducated), 20 or above for primary education (6 years of education).
Exclusion criteria
Exclusion criteria: 1.Before the surgery, due to coma, severe dementia or language disorders, communication was impossible. 2.Those who had a clear history of neurological diseases, mental illness, or abnormal personality, such as schizophrenia, depression, epilepsy, Parkinson's disease, multiple sclerosis, etc. 3.There were severe abnormalities in heart, brain, kidney, and liver functions. 4.There was a history of drug dependence or alcohol abuse. 5. Within one week before the sampling, they had used drugs or methods that might affect the oral microbiota, such as immunosuppressants, hormone drugs, antibacterial drugs, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Countries
China
Contacts
Eastern Theater Command General Hospital