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Impact of Oral Frailty on Postoperative Delirium in Elderly Patients: Mechanisms and Implications

Impact of Oral Frailty on Postoperative Delirium in Elderly Patients: Mechanisms and Implications

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102169
Enrollment
Unknown
Registered
2025-05-09
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Observation Group:None

Sponsors

Eastern Theater Command General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. ASA classification I-III; 2. Age >= 65 years; 3. Scheduled surgery with planned subarachnoid block anesthesia; 4. Preoperative screening using the Mini-Mental State Examination (MMSE) (maximum score 30), with scores of 17 or above for illiterate (uneducated), 20 or above for primary education (6 years of education).

Exclusion criteria

Exclusion criteria: 1.Before the surgery, due to coma, severe dementia or language disorders, communication was impossible. 2.Those who had a clear history of neurological diseases, mental illness, or abnormal personality, such as schizophrenia, depression, epilepsy, Parkinson's disease, multiple sclerosis, etc. 3.There were severe abnormalities in heart, brain, kidney, and liver functions. 4.There was a history of drug dependence or alcohol abuse. 5. Within one week before the sampling, they had used drugs or methods that might affect the oral microbiota, such as immunosuppressants, hormone drugs, antibacterial drugs, etc.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;

Countries

China

Contacts

Public ContactShen Jinchun

Eastern Theater Command General Hospital

yyshen0203@163.com+86 158 9599 0011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026