Chronic periodontitis, primary IgA nephropathy
Conditions
Interventions
Control group:Periodontal treatment in Western medicine
Experimental group:Periodontal treatment combined with the treatment of Yashushenning Gargle
Control blank group :Oral health education
Sponsors
Hangzhou Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years, no pregnancy or breastfeeding; 2. No bad habits such as drinking or smoking; 3. No patients with poorly controlled systemic diseases such as hypertension, coronary heart disease, or diabetes; 4. Primary IgAN receiving standard treatment, with no recent changes in condition; 5. Proteinuria less than 1.0, GFR greater than 60, no history of hormone use in the past six months, no history of periodontal treatment; 6. At least 20 teeth remaining in the mouth.
Exclusion criteria
Exclusion criteria: 1. Active urinary tract infection, severe acute infection episodes of kidney disease and oral diseases; 2. Received immunosuppressive treatment within the past 3 months (including but not limited to cyclophosphamide, mycophenolate mofetil, etc.); 3. Long-term use of non-steroidal anti-inflammatory drugs (for over 1 month) or history of bisphosphonate drugs; presence of severe oral mucosal lesions; 4. Severe cognitive impairment or mental illness that makes cooperation in treatment and follow-up impossible; 5. Participation in other clinical interventional studies within the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal function test; | — |
Secondary
| Measure | Time frame |
|---|---|
| urinalysis;Indices related to oxidative stress;Periodontal indices; | — |
Countries
China
Contacts
Public ContactQian Zhang
Hangzhou Hospital of Traditional Chinese Medicine
Outcome results
None listed