Diabetic neuropathic pain
Conditions
Interventions
Group E1:After the patient was admitted to the room, the sacral plexus nerve block was given under ultrasound guidance, and after the successful block, the E1 group was given a single intravenous admi
Group E2:The patient was given sacral plexus nerve block under ultrasound guidance after admission, and after successful block, E2 group was given a single intravenous administration of esketamine 0.5
Group N:After entering the room, the patient was given sacral plexus nerve block under ultrasound guidance, and after successful block, group N was given a single intravenous saline of 10ml.
Sponsors
Zhu Xianyi Memorial Hospital, Tianjin Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Diabetic foot debridement is planned to be performed under nerve block anesthesia with a clear diagnosis of diabetic foot and NP; (2) Age >=18 years old, gender is not limited; (3) ASA classification II.-III; (4) The patient is informed and voluntarily joins and signs the consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who do not meet the inclusion criteria; (2) Patients with contraindications to ketamine, including impaired consciousness, neuropsychiatric history, severe cardiovascular history, poorly controlled or untreated hypertension or hyperthyroidism, pregnancy or lactation; (3) Those who have a known history of severe allergies and family history or are allergic to ketamine; (4) Those who have used non-steroidal anti-inflammatory drugs or opioid analgesics within 48 hours before surgery; (5) Patients or their family members who refuse to participate in the study and whose data are incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mechanical pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| The onset time and duration of sensation and motor block;Postoperative recovery quality;Patient pain score;Intraoperative hemodynamic indicators of patients;General information of the patient (age, gender, weight, BMI, ASA grading, underlying diseases); | — |
Countries
China
Contacts
Public ContactJing Gong
Zhu Xianyi Memorial Hospital, Tianjin Medical University
Outcome results
None listed