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Research on Corneal Stem Cell Niche Homeostasis and Corneal Injury Repair in Ocular Chronic Graft-versus-Host Disease Based on Multi-Omics

Research on Corneal Stem Cell Niche Homeostasis and Corneal Injury Repair in Ocular Chronic Graft-versus-Host Disease Based on Multi-Omics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102131
Enrollment
Unknown
Registered
2025-05-09
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic graft-versus-host disease

Interventions

Enucleation group:None

Sponsors

The Second Affiliated Hospital of the Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Clear indications for surgery, such as severe eye injury, absolute glaucoma, etc.; 2. 18 years < = patient age< = 70 years; 3. There is no restriction on the gender of the patient; 4. The patient is in good physical and mental condition and can tolerate enucleation; 5. Informed consent: Patients or their legal guardians voluntarily sign the informed consent form after fully understanding this study.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing enucleation due to uncontrollable infections such as endophthalmitis; 2.Patients undergoing enucleation due to ocular malignancies; 3.Any other situations in which the investigators consider the patient ineligible for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
None;—

Countries

China

Contacts

Public ContactZhang Xi

The Second Affiliated Hospital of the Army Medical University

zhangxxi@sina.com+86 23 68763198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026