remifentanil-induced postoperative hyperalgesia
Conditions
Interventions
Sponsors
Fujian Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: Aged 18-49 years, ASA physical status I-II, with a history of regular menstrual cycles of 28-32 days, candidates for laparoscopy under general anesthesia for benign gynecological pathologies
Exclusion criteria
Exclusion criteria: 1. Irregular menstruation 2. serious heart disease,brain, kidney, lung, and other organ system diseases 3. pregnancy or lactation 4. history of chronic pain 5. analgesic use within one month before surgery 6. history of heavy smoking or alcohol abuse 7. underweight (body mass index, BMI 30 kg/m^2) 8. inability to follow the study procedure 9. allergy to opioids 10. intraoperative conversion to laparotomy or a second operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mechanical hyperalgesia in the forearm; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical hyperalgesia in the incision;The maximum pain NRS score;total analgesic consumption;Relevant side effects;QoR - 15; | — |
Countries
China
Contacts
Public ContactLijun Yang
Fujian Maternity and Child Health Hospital; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University
Outcome results
None listed