None
Conditions
Interventions
Dex group:None
Shame group:None
Sponsors
Fujian Children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Children undergoing surgery in Fujian Children's Hospital. (2)From umbilical cord ligation to 28 days after birth (gestational age =28 weeks), gender is not limited, ASA grade II-III. (3)Invasive hemodynamic monitoring is possible. (4)The guardian gives informed consent and signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) There were severe neurological complications before operation, such as severe intraventricular hemorrhage and periventricular leukomalacia. (2) Very low birth weight infants <=1000g; (3) Genetic or chromosomal diseases, major cardiac malformations (except small patent ductus arteriosus or patent foramen ovale), or organ malformations. (4) Severe organ failure after operation. (5) Incomplete and unqualified medical records. (6) Giving up treatment or transferring to another hospital during the study period. (7) Refusal to follow up or loss of follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bayley scales of infant and toddler development-third edition, Bayley-?;Amplitude-integrated electroencephalography,aEEG;Cerebral oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-1ß;IL-6;TNF-a;Tau protein; | — |
Countries
China
Contacts
Public ContactGuolin Lu
Fujian Children’s Hospital
Outcome results
None listed