painless gastroscopy
Conditions
Interventions
Non-gender group:Upon entering the examination room, the patients underwent standard monitoring before receiving a gradual intravenous infusion of remifentanil at a rate of 0.5µg/kg,followed by an in
if not,it was decreased by the same amount.The point at which positive reactions transitioned to negative ones was identified as the crossover point, with the study concluding after seven crossover po
Male group:Upon entering the examination room, the patients underwent standard monitoring before receiving a gradual intravenous infusion of remifentanil at a rate of 0.5µg/kg,followed by an initial i
Female group:Upon entering the examination room, the patients underwent standard monitoring before receiving a gradual intravenous infusion of remifentanil at a rate of 0.5µg/kg,followed by an initial
Sponsors
The First Affiliated Hospital of Xi'an Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients set to undergo painless gastroscopy; 2. Age 65 years or older; 3. American Society of Anesthesiologists (ASA) classification levels I-III; 4. remimazolam and femifentanil were useded.
Exclusion criteria
Exclusion criteria: 1. Previous allergic reactions to benzodiazepines or their ingredients; 2. Chronic alcohol or drug addiction; 3. Schizophrenia and major depressive disorder; 4. Severe obesity and obstructive sleep apnea; 5. Recent upper respiratory infections or worsening asthma; 6. Uncontrolled high blood pressure or unstable angina; 7. Significant liver impairment, acute upper GI bleeding with shock, severe anemia, or gastrointestinal blockage with retained gastric contents; 8. Angle-closure glaucoma; 9. History of prolonged use of sedatives and pain relievers; 10. Myasthenia gravis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| half-effective dose;95% effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;arterial pressure;espiratory rate;oxygen saturation;adverse reaction; | — |
Countries
China
Contacts
Public ContactDanni Lyu
The First Affiliated Hospital of Xi'an Medical University
Outcome results
None listed