Choroidal neovascularization
Conditions
Interventions
This study included a total of 84 patients with various diseases that induce CNV, including AMD (Age-related Macular Degeneration), PM-CNV (Polypoidal Choroidal Vasculopathy-associated CNV), and idiop
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Presence of CNV (Including AMD, PM-CNV, and Idiopathic CNV): Confirmation of CNV Based on a Combination of Various Imaging Modalities Including Fundus Photography, Optical Coherence Tomography (OCT), Optical Coherence Tomography Angiography (OCTA), and Fluorescein Angiography (FFA); 2.PM-CNV (Polypoidal Choroidal Vasculopathy with Choroidal Neovascularization) necessitates meeting the diagnostic criteria for pathologic myopia, which include a refractive error equivalent spherical power of greater than -6.00 diopters (D) or an axial length exceeding 26.00 mm, accompanied by typical scleral, choroidal, and retinal pathologies.
Exclusion criteria
Exclusion criteria: 1.Due to opacities in the refractive media, the image quality of FFA or OCTA is compromised. 2.Patients with coexisting glaucoma, ocular trauma, and other fundus oculi pathologies, who have undergone previous intraocular surgical interventions. 3.Patients in whom CNV cannot be identified by OCTA. 4.Patients with coexisting systemic diseases, including diabetes mellitus, hypertension, coronary heart disease, cerebral infarction, and other conditions that affect retinal blood supply. 5. On the OCTA image, the area of the CNV is not within the central 3 × 3mm^2, or the CNV area is too large and exceeds the central 3 × 3mm^2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vessel Density of OCTA;Fluorescence leakage index of CNV on FFA;Fluorescence intensity index of CNV on FFA; | — |
Countries
China
Contacts
Public ContactLv Zhe
Eye Hospital, Wenzhou Medical University
Outcome results
None listed