Liver failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Between 18 and 65 years old; 2. AST/ALT>20 times ULN; 3. TBIL>10 x ULN; 4. PT-INR> 1.5; 5. PLT>50×10^9/L; 6. Liver imaging showed no liver cancer;
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with HIV infection or other immunodeficiency diseases; 3. Patients with diabetes, autoimmune diseases, infarction caused by cardiovascular and cerebrovascular accidents, history of organ transplantation and other organs Dysfunction or failure; 4. Patients with active bleeding, diffuse intravascular coagulation, thrombosis or thrombotic disease; 5. Those who cannot comply with the study arrangement and sign the informed consent; 6. Can not return to the hospital regularly according to the study plan and follow up visitors; 7. Other conditions that the researchers judged were not suitable for inclusion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation function;MELD score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions (e.g. local hypersensitivity, extubation, local bleeding, shock, death, etc.);Renal function;Blood routine examination;Liver function; | — |
Countries
China
Contacts
Affiliated Hospital of Guangdong Medical University