Study on the Effects of Eye Pressure Changes on the Optic Nerve in High Myopia with Glaucoma

Dynamic Observation of Optic Nerve Head Biomechanics and Blood Flow Characteristics under Intraocular Pressure Variation in High Myopia Combined with Glaucoma

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500102103

Enrollment

Unknown

Registered

2025-05-08

Start date

2025-06-01

Completion date

Unknown

Last updated

2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Myopia Combined with Open-Angle Glaucoma

Interventions

High myopia group:High myopia

Normal control:None

High Myopia with Open-Angle Glaucoma:High myopia with open angle glaucoma

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Adults aged between 18 and 70 years. 2.Meet the specific diagnostic criteria for the respective categories. 3.Intraocular pressure (IOP) <= 21 mmHg. 4.No other severe ocular diseases (e.g., cataract, corneal disease, retinal disease, etc.). 5.Good language ability and willingness to cooperate, able to comply with the experimental procedures.

Exclusion criteria

Exclusion criteria: 1.Ocular history of optic nerve head lesions or other retinal diseases. 2.Pregnant or breastfeeding women. 3.Patients withsystemic diseases affecting ocular structure or blood flow (e.g., diabetes, hypertension, etc.). 4. Patients who are unable to obtain reliable data during ophthalmic examination or OCT/A image acquisition.

Design outcomes

Primary

Measure	Time frame
ONH structure;	—

Countries

China

Contacts

Public ContactMeixiao Shen

Eye Hospital, Wenzhou Medical University

smx77@sohu.com+86 158 0587 4558

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026