Skip to content

A retrospective study of photodynamic therapy for oral erythroplakia

A retrospective study of photodynamic therapy for oral erythroplakia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102089
Enrollment
Unknown
Registered
2025-05-08
Start date
2024-07-01
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral erythroplakia

Interventions

photodynamic therapy:NA

Sponsors

Hospital of Stomatology Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with oral erythroplakia who sought treatment at the Oral Disease Department of Wuhan University School of Stomatology from November 2019 to April 2024, with clinical manifestations that meet the definition of oral erythroplakia set forth in the "Expert Consensus on Clinical Diagnosis and Treatment of Oral Erythroplakia" issued by the Chinese Stomatological Association in 2023, including the following: A) Clinical manifestations of homogeneous and heterogeneous erythema lesions. Homogeneous lesions are characterized by soft, smooth, velvety bright red surfaces with well-defined margins. Heterogeneous lesions are characterized by red patches scattered within the lesion area, with red and white patches alternating. B) Histopathological findings that exclude other definable diseases, characterized by marked epithelial atrophy, accompanied by varying degrees of epithelial dysplasia, consistent with the diagnosis of oral erythroplakia. 2.Patients aged 18 to 80 years old; 3.Patients received and completed at least one session of photodynamic therapy; 4.Regular follow-up more than 3 months;

Exclusion criteria

Exclusion criteria: 1.The initial pathological results of the patients showed carcinoma in situ or invasive carcinoma; 2.Clinical follow-up records or information is not complete;

Design outcomes

Primary

MeasureTime frame
recurrence rate;malignant transformation rate;efficacy;

Secondary

MeasureTime frame
adverse effects rate;

Countries

China

Contacts

Public ContactLu Rui

Hospital of Stomatology Wuhan University

lurui@whu.edu.cn+86 27 87686213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026