Painless gastroscopy and colonoscopy
Conditions
Interventions
Experimental group:Oxelidine 1-2mg+ propofol 2mg/kg
Control group:The butorphanol group was given butorphanol 0.6mg (or 0.02mg/kg) + propofol 2mg/kg
Sponsors
Jintang County First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-50 years old, gender not limited; 2. Body mass index: 18.5-27.9kg/m ² 3. The ASA classification is grade I-II; 4. Inspection time <=60 minutes; 5. Patients who are scheduled to undergo gastroscopy and colonoscopy 6. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to endoscopic operations or those who refuse anesthesia; 2. Those who have contraindications or allergies to the test drug or other anesthetic drugs; 3. Uncontrolled circulatory and respiratory system diseases that may threaten life, such as acute coronary syndrome, uncontrolled severe hypertension (systolic blood pressure >=180mmHg, diastolic blood pressure >=110mmHg), severe arrhythmia, heart failure, acute respiratory tract infection, asthma attack period, active massive hemoptysis Liver dysfunction (Child-Pugh grade C or above), acute upper gastrointestinal bleeding with shock, severe anemia (Hb<6g/dl), gastrointestinal obstruction with retention of gastric contents; 4. Patients who participated in other studies within 30 days; 5. The researcher believes that there are other reasons that make participation in this clinical trial inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of adverse events of respiratory depression (SPO2<90%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators;The frequency of body movement and choking cough during the examination;Drug dosage;The number of additional doses of propofol; | — |
Countries
China
Contacts
Public ContactLi Deyuan
Jintang County First People's Hospital
Outcome results
None listed